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Administered doses ranged from 12.5 to 100 µg rBet v 1. Serum rBet v1 specific IgE ELISA and birch radioallergosorbent testing were performed. Results: After 5.5 months, rBet v1 and rMal dl specific IgA levels had increased from baseline in the LGG compared with the placebo group (delta rBet v1 IgA, 0.319 vs. -0.136 relative units; P = .02; delta rMal d1 IgA, 0.097 vs -0.117, P = .02). rBet v1 specific IgE serum levels did not differ between the groups.

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